IFITM2 Antibodies, cDNA Clones Research Reagents

IFITM2 (Interferon Induced Transmembrane Protein 2, also known as 1-8D; DSPA2c), located on 11p15.5, is a Protein Coding gene. The gene produces a 14632 Da protein composed of 132 amino acids. That IFITM2 is a novel prognostic biomarker and regulator of GC progression. The IFITM2 protein, which is approximately 90% identical to IFITM3, has an N-terminal signal sequence, 3 potential phosphorylation sites, and a C-terminal leucine zipper. Diseases such as Cycloplegia and Influenza are associated with IFITM2. The related pathways of IFITM2 include Interferon gamma signaling and the Innate Immune System.

IFITM2 Antibody (1)

    IFITM2 cDNA Clone (27)

    NM_006435.2

    クローニングベクター cDNA 製品

    BC084679.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_030833.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    IFITM2 qPCR Primer (1)

    IFITM2 の背景知識

    IFITM2 (Interferon Induced Transmembrane Protein 2) is a Protein Coding gene. The encoded protein IFITM2 belongs to the CD225/Dispanin family. IFITM2 knockdown decreased GC cell proliferation, migration, invasion, and epithelial-to-mesenchymal transition in vitro. And IFITM2 expression was in part induced by insulin-like growth factor (IGF) 1 via IGF1 receptor/signal transducer and activator of transcription 3 signaling. Furthermore, IFITM2 regulated interleukin-6 expression and secretion, which in turn increased IFITM2 expression. Silencing of IFITM2 expression suppressed tumor growth and lung metastasis in vivo. That IFITM2 is a novel prognostic biomarker and regulator of GC progression. IFITM2 is widely expressed in the appendix, spleen, and other tissues. Diseases associated with IFITM2 include Cycloplegia and Influenza.

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