Iba1 Proteins, Antibodies, cDNA Clones Research Reagents

All Iba1 reagents are produced in house and quality controlled, including 7 Iba1 Antibody, 15 Iba1 Gene, 2 Iba1 IP Kit, 1 Iba1 Protein, 1 Iba1 qPCR. All Iba1 reagents are ready to use.

Iba1 Protein (1)

    Iba1 Antibody (7)

      Iba1 cDNA Clone (15)


      クローニングベクター cDNA 製品

      In lentiviral vector

      Iba1 qPCR Primer (1)

      Iba1 の背景知識

      AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

      Iba1 の参考文献

      • Albertella M.R., et al.,(1994), Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins. Hum. Mol. Genet. 3:793-799.
      • Holzinger I., et al., (1995), Cloning and genomic characterization of LST1: a new gene in the human TNF region.Immunogenetics 42:315-322.
      • Autieri M.V., et al.,(1996), cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries.Biochem. Biophys. Res. Commun. 228:29-37.

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