GSR/Glutathione reductase Antibodies, cDNA Clones Research Reagents

GSR (Glutathione-Disulfide Reductase, also known as GR; GSRD; HEL-75; HEL-S-122m), located on 8p12, is a Protein Coding gene. The gene produces a 56257 Da protein composed of 522 amino acids. As part of the glutathione redox cycle, GSR plays a role in the detoxification of reactive oxygen species. It is also involved in some cellular functions including the activation of dormant cells and the regulation of the cell cycle. Diseases such as Hemolytic Anemia Due To Glutathione Reductase Deficiency and Riboflavin Deficiency are associated with GSR.

GSR/Glutathione reductase Antibody (2)

    GSR/Glutathione reductase cDNA Clone (15)


    クローニングベクター cDNA 製品

    In lentiviral vector

    GSR/Glutathione reductase qPCR Primer (1)

    GSR/Glutathione reductase の背景知識

    GSR (Glutathione-Disulfide Reductase) is a Protein Coding gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. GSR, a key member of the glutathione antioxidant defense system, converts oxidized glutathione (GSSG) to reduced glutathione (GSH) and maintains the intracellular glutathione redox state to protect the cells from oxidative damage. It is a central enzyme of cellular antioxidant defense. Under normal physiological conditions, GSR is not essential for the maintenance of antioxidant defenses in the mouse cochlea. The antioxidant enzyme GSR gene polymorphisms are significantly associated with bone mineral density (BMD). Diseases associated with GSR include Hemolytic Anemia Due To Glutathione Reductase Deficiency and Riboflavin Deficiency.

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