GPR133 Proteins, Antibodies, cDNA Clones Research Reagents

ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as PGR25; GPR133), located on 12q24.33, is a Protein Coding gene. The gene produces a 96530 Da protein composed of 874 amino acids. ADGRD1, an orphan member of the adhesion family of G-protein-coupled receptors (GPCRs), is a critical regulator of the response to hypoxia and tumor growth in Glioblastoma (GBM). The adhesion GPCRs, including ADGRD1, are membrane-bound proteins with long N termini containing multiple domains. The related pathways of ADGRD1 include GPCRs, Other.

GPR133 Protein (1)

    GPR133 Antibody (1)

      GPR133 cDNA Clone (13)

      BC112309

      クローニングベクター cDNA 製品

      In lentiviral vector

      GPR133 qPCR Primer (1)

      GPR133 Lysate (1)

        GPR133 の背景知識

        ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1, an orphan member of the adhesion family of G-protein-coupled receptors, is a critical regulator of the response to hypoxia and tumor growth in Glioblastoma (GBM). ADGRD1 represents a novel molecular target in GBM and possibly other malignancies where hypoxia is fundamental to pathogenesis. Variations in the ADGRD1 locus are linked with differences in metabolism, human height, and heart frequency. ADGRD1 is a Gs protein-coupled receptor belonging to the class of adhesion GPCRs. The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains.

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