GMPR Proteins, Antibodies, cDNA Clones Research Reagents

All GMPR reagents are produced in house and quality controlled, including 1 GMPR Antibody, 32 GMPR Gene, 1 GMPR Protein, 2 GMPR qPCR. All GMPR reagents are ready to use.

GMPR Protein (1)

    GMPR Antibody (1)

      GMPR cDNA Clone (32)

      BC008281

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_025508.4

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_057188.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      GMPR の背景知識

      GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

      GMPR の参考文献

      • Deng Y., et al.,(2002), NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties. Int. J. Biochem. Cell Biol. 34:1035-1050.
      • Zhang J., et al., (2003), Cloning and functional characterization of GMPR2, a novel human guanosine monophosphate reductase, which promotes the monocytic differentiation of HL-60 leukemia cells.J. Cancer Res. Clin. Oncol. 129:76-83.
      • Ivens A.C., et al.,(2005), The genome of the kinetoplastid parasite, Leishmania major.Science 309:436-442.

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