GCSH Proteins, Antibodies, cDNA Clones Research Reagents

All GCSH reagents are produced in house and quality controlled, including 6 GCSH Antibody, 30 GCSH Gene, 1 GCSH Protein, 1 GCSH qPCR. All GCSH reagents are ready to use.

GCSH Protein (1)

    GCSH Antibody (6)

      GCSH cDNA Clone (30)

      BC000790

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_026572.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      GCSH qPCR Primer (1)

      GCSH の背景知識

      Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for GCSH gene. Also, several transcribed and non-transcribed pseudogenes of GCSH gene exist throughout the genome.

      GCSH の参考文献

      • Hiraga K. et al., 1988, Biochem Biophys Res Commun. 151 (2): 758-62.
      • Fujiwara K. et al., 1991, Biochem Biophys Res Commun. 176 (2): 711-6.
      • Koyata H. et al., 1991, Am J Hum Genet. 48 (2): 351-61.

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