GBP2 Proteins, Antibodies, cDNA Clones Research Reagents

All GBP2 reagents are produced in house and quality controlled, including 2 GBP2 Antibody, 15 GBP2 Gene, 1 GBP2 Lysate, 1 GBP2 Protein, 1 GBP2 qPCR. All GBP2 reagents are ready to use.

GBP2 Protein (1)

    GBP2 Antibody (2)

      GBP2 cDNA Clone (15)


      クローニングベクター cDNA 製品

      In lentiviral vector

      GBP2 qPCR Primer (1)

      GBP2 Lysate (1)

        GBP2 の背景知識

        GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interferons that have antiviral effects and inhibit tumor cell proliferation.

        GBP2 の参考文献

        • Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
        • Wistow G, et al. (2002) Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. Mol Vis. 8:205-20.
        • Neun R, et al. (1996) GTPase properties of the interferon-induced human guanylate-binding protein 2. FEBS Lett. 390(1):69-72.

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