Fucose Mutarotase Proteins, Antibodies, cDNA Clones Research Reagents

All Fucose Mutarotase reagents are produced in house and quality controlled, including 1 Fucose Mutarotase Antibody, 15 Fucose Mutarotase Gene, 1 Fucose Mutarotase Protein, 1 Fucose Mutarotase qPCR. All Fucose Mutarotase reagents are ready to use.

Fucose Mutarotase Protein (1)

    Fucose Mutarotase Antibody (1)

      Fucose Mutarotase cDNA Clone (15)


      クローニングベクター cDNA 製品

      In lentiviral vector

      Fucose Mutarotase qPCR Primer (1)

      Fucose Mutarotase の背景知識

      FUOM, also known as fucose mutarotase and FucM, belongs to the RbsD / FucU family. FUOM is involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose has two isforms: alpha-L-fucose (29.5%) and beta-L-fucose (7.5%). The beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. FUOM mainly exists as homodimer, but also functions as homotetramer, homooctamer, and homodecamer. FUOM's homodimeric form seems catalytically inactive.

      Fucose Mutarotase の参考文献

      • Deloukas P. et al., 2004, Nature. 429: 375-81.
      • Ota T. et al., 2004, Nat Genet. 36: 40-5.
      • Dongkyu Park. et al., 2007, Glycobiology. 17 (9): 955-62.

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