FGF9 Proteins, Antibodies, cDNA Clones Research Reagents

All FGF9 reagents are produced in house and quality controlled, including 1 FGF9 Antibody, 52 FGF9 Gene, 2 FGF9 Lysate, 2 FGF9 Protein, 3 FGF9 qPCR. All FGF9 reagents are ready to use.

FGF9 Protein (2)

    FGF9 Antibody (1)

      FGF9 cDNA Clone (52)

      NM_002010.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_013518.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_012952.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      XM_844845.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      FGF9 Lysate (2)

        FGF9 の背景知識

        Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. FGF9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF9 may have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.

        FGF9 の参考文献

        • Giri D, et al. (1999) FGF9 is an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells. J Cell Physiol. 180(1): 53-60.
        • Schmahl J, et al. (2004) Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development. 131(15): 3627-36.
        • Garcès A, et al. (2000) FGF9: a motoneuron survival factor expressed by medial thoracic and sacral motoneurons. J Neurosci Res. 60(1): 1-9.

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