FABP3 Proteins, Antibodies, cDNA Clones Research Reagents

All FABP3 reagents are produced in house and quality controlled, including 2 FABP3 Antibody, 47 FABP3 Gene, 1 FABP3 IP Kit, 2 FABP3 Protein, 3 FABP3 qPCR. All FABP3 reagents are ready to use.

FABP3 Protein (2)

    FABP3 Antibody (2)

      FABP3 cDNA Clone (47)

      NM_004102.3

      In expression vector

      In lentiviral vector

      AK142156.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_024162.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      XM_005544157.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      FABP3 の背景知識

      Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular signaling and gene transcription. Previously FABP3 was involved in apoptosis-associated congenital cardiac malformations. FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function, which may be responsible for the knockdown of FABP3-induced apoptosis. FABP3 as a candidate gene underlying the etiology of congenital heart defects. Overexpression of FABP3 inhibited cell growth and proliferation via negative regulation of the cell cycle and down-regulation of cell growth factors, but enhances cell survival in hypoxic or ischemic conditions. FABPs are known to be carrier proteins for transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus, where these lipids are released to a group of nuclear receptors such as peroxisome proliferator-activated receptors (PPARs).

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