ESRP1/RBM35A Proteins, cDNA Clones Research Reagents

All ESRP1/RBM35A reagents are produced in house and quality controlled, including 15 ESRP1/RBM35A Gene, 1 ESRP1/RBM35A Lysate, 1 ESRP1/RBM35A Protein, 1 ESRP1/RBM35A qPCR. All ESRP1/RBM35A reagents are ready to use.

ESRP1/RBM35A Protein (1)

    ESRP1/RBM35A cDNA Clone (15)

    NM_017697.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    ESRP1/RBM35A qPCR Primer (1)

    ESRP1/RBM35A Lysate (1)

      ESRP1/RBM35A の背景知識

      Epithelial splicing regulatory protein 1 (ESRP1) is an epithelial cell-specific RNA binding protein that controls several key cellular processes, like alternative splicing and translation. Epithelial splicing regulatory protein 1 (ESRP1) has been characterized as an essential splicing factor required for the regulation of human pluripotency and differentiation. ESRP1 regulates CD44 alternative splicing during the EMT process which plays an important role in EOC carcinogenesis. In addition, ESRP1 is associated with disease prognosis in epithelial ovarian cancer (EOC). Epithelial splicing regulatory protein 1 (ESRP1) and 2 (ESRP2), epithelial cell-specific regulators of alternative splicing, are downregulated during the epithelial-mesenchymal transition (EMT). There is a critical role of the AS regulator epithelial splicing regulator protein 1 (ESRP1) for intestinal homeostasis and pathogenesis.

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