EPOR Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All EPOR reagents are produced in house and quality controlled, including 9 EPOR Antibody, 2 EPOR ELISA, 26 EPOR Gene, 4 EPOR Lysate, 4 EPOR Protein, 2 EPOR qPCR. All EPOR reagents are ready to use.

EPOR Protein (4)

    EPOR Antibody (9)

      EPOR ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(2)

      EPOR cDNA Clone (26)

      NR_033663.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_010149.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      EPOR Lysate (4)

        EPOR の背景知識

        Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

        EPOR の参考文献

        • Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
        • Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
        • Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.

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