ENO1 Proteins, Antibodies, cDNA Clones Research Reagents

All ENO1 reagents are produced in house and quality controlled, including 6 ENO1 Antibody, 87 ENO1 Gene, 2 ENO1 IP Kit, 2 ENO1 Protein, 2 ENO1 qPCR. All ENO1 reagents are ready to use.

ENO1 Protein (2)

    ENO1 Antibody (6)

      ENO1 cDNA Clone (87)

      NM_001428.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_023119.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_012554.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      XM_002716143.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      XM_004768617.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001195611.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      ENO1 qPCR Primer (2)

      ENO1 の背景知識

      The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make the primary culture follicle granulosa cells in vitro improve progesterone secretion. The over-expression of ENO1 protein can enhance the abilities of proliferation and migration in gastric cancer cells of AGS, which indicates that ENO1 may be an important potential tumor-marker associated with the development of gastric cancer. ENO1 and GPI can be used as markers of human sperm freezability before starting the cryopreservation procedure. The inhibition of ENO1 expression may be a novel strategy for therapy for NHLs patients, and it may be a target for drug resistance.

      ENO1 の参考文献

      • Capello M, et al. (2011) a-Enolase: a promising therapeutic and diagnostic tumor target. FEBS J. 278(7): 1064-74.
      • Kang HJ, et al. (2008) Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme. Acta Crystallogr D Biol Crystallogr. 64(Pt 6): 651-7.
      • Lopez-Alemany R, et al. (2005) Alpha-enolase plasminogen receptor in myogenesis. Front Biosci. 10: 30-6.
      • Ejeskdr K, et al. (2005) Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death. BMC Cancer. 5: 161.

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