Endothelin A Receptor Antibodies, cDNA Clones Research Reagents

All Endothelin A Receptor reagents are produced in house and quality controlled, including 1 Endothelin A Receptor Antibody, 17 Endothelin A Receptor Gene, 1 Endothelin A Receptor qPCR. All Endothelin A Receptor reagents are ready to use.

Endothelin A Receptor Antibody (1)

    Endothelin A Receptor cDNA Clone (17)

    BC022511

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_010332.2

    In expression vector

    In lentiviral vector

    NM_012550.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    Endothelin A Receptor qPCR Primer (1)

    Endothelin A Receptor の背景知識

    The product of EDNRA, endothelin receptor A, is a G protein-coupled receptor that causes cellular proliferation and contraction (26, 27) of smooth muscle when ligated to endothelin. Polymorphisms in this gene have been associated with variation in vascular phenotypes stemming from vasoconstriction.This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

    Endothelin A Receptor の参考文献

    • Darrah R, McKone E, O'Connor C, et al. EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity[J]. Physiological genomics, 2010, 41(1): 71-77.

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