EIF5A2 Proteins, Antibodies, cDNA Clones Research Reagents

All EIF5A2 reagents are produced in house and quality controlled, including 3 EIF5A2 Antibody, 15 EIF5A2 Gene, 2 EIF5A2 IP Kit, 1 EIF5A2 Protein, 1 EIF5A2 qPCR. All EIF5A2 reagents are ready to use.

EIF5A2 Protein (1)

    EIF5A2 Antibody (3)

      EIF5A2 cDNA Clone (15)

      BC036072

      クローニングベクター cDNA 製品

      In lentiviral vector

      EIF5A2 qPCR Primer (1)

      EIF5A2 の背景知識

      Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic target for the treatment of NSCLC. EIF5A2 might be a novel therapeutic target for the inhibition of NPC progress. EIF5A2 overexpression may contribute to cancer progression and poor prognosis, it could be a novel potential prognostic marker for FIGO stage I-II cervical cancer. EIF5A2 upregulation plays an important oncogenic role in gastric cancer. EIF5A2 may represent a new predictor for poor survival and is a potential therapeutic target for gastric cancer. The eukaryotic initiation factor 5A2 (EIF5A2) over-expression enhances HCC cell metastasis. EIF5A2, as a target of PI3K/Akt, promotes melanoma cell invasion and may serve as a promising prognostic marker and a potential therapeutic target for melanoma.

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