DPYS Proteins, cDNA Clones Research Reagents

All DPYS reagents are produced in house and quality controlled, including 45 DPYS Gene, 2 DPYS Lysate, 2 DPYS Protein, 1 DPYS qPCR. All DPYS reagents are ready to use.

DPYS Protein (2)

    DPYS cDNA Clone (45)

    BC034395

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_001164466.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    XM_003639441.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    DPYS qPCR Primer (1)

    DPYS Lysate (2)

      DPYS の背景知識

      DPYS, also known as dihydropyrimidinase, belongs to the DHOase family, hydantoinase/dihydropyrimidinase subfamily. DPYS catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. It can catalyzes the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. DPYS is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

      DPYS の参考文献

      • Thomas HR. et al., 2008, Genomics. 18 (1): 25-35.
      • Thomas HR. et al., 2008, Pharmacogenet Genomics. 17 (11): 973-87.
      • Van Kuilenburg AB. et al., 2007, Mol Genet Metab. 91 (2): 157-64.

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