DKK3 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All DKK3 reagents are produced in house and quality controlled, including 8 DKK3 Antibody, 3 DKK3 ELISA, 15 DKK3 Gene, 1 DKK3 Lysate, 1 DKK3 Protein, 2 DKK3 qPCR. All DKK3 reagents are ready to use.

DKK3 Protein (1)

    DKK3 Antibody (8)

      DKK3 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(3)

      DKK3 cDNA Clone (15)


      In expression vector


      クローニングベクター cDNA 製品

      In lentiviral vector

      DKK3 Lysate (1)

        DKK3 の背景知識

        DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

        DKK3 の参考文献

        • Yue W, et al., 2008. Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis, 29 (1): 84-92.
        • Ding Z, et al., 2009. Promoter methylation and mRNA expression of DKK3 and WIF-1 in hepatocellular carcinoma. World J Gastroenterol, 15 (21):2595-601.

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