DHRS3 Antibodies, cDNA Clones Research Reagents

All DHRS3 reagents are produced in house and quality controlled, including 2 DHRS3 Antibody, 26 DHRS3 Gene, 1 DHRS3 qPCR. All DHRS3 reagents are ready to use.

DHRS3 Antibody (2)

    DHRS3 cDNA Clone (26)

    NM_004753.5

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_011303.6

    クローニングベクター cDNA 製品

    In lentiviral vector

    DHRS3 qPCR Primer (1)

    DHRS3 の背景知識

    Dehydrogenase/reductase (SDR family) member 3 (DHRS3), also known as retinal short-chain dehydrogenase/reductase (retSDR1) is a member of SDR16C family. Retinol and its metabolites have important roles in many processes including embryonic development, cellular differentiation, apoptosis and maintenance of epithelia. Retinal short-chain dehydrogenase/reductase retSDR1, also known as dehydrogenase/reductase member 3 (DHRS3), is involved in maintaining the cellular supply of retinol metabolites. DHRS3 is an endoplasmic reticulum (ER) protein that is shuttled to the ER via an N-terminal endoplasmic reticulum targeting signal. The retinoic acid-inducible dehydrogenase reductase 3 (DHRS3) is thought to function as a retinaldehyde reductase that controls the levels of all-trans-retinaldehyde, the immediate precursor for bioactive all-trans-retinoic acid. However, the weak catalytic activity of DHRS3 and the lack of changes in retinaldehyde conversion to retinol and retinoic acid in the cells overexpressing DHRS3 undermine its role as a physiologically important all-trans-retinaldehyde reductase.

    Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.