Desmin Antibodies, cDNA Clones Research Reagents

All Desmin reagents are produced in house and quality controlled, including 6 Desmin Antibody, 45 Desmin Gene, 1 Desmin IP Kit, 1 Desmin qPCR. All Desmin reagents are ready to use.

Desmin Antibody (6)

    Desmin cDNA Clone (45)

    BC032116

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_010043.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_022531.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    Desmin qPCR Primer (1)

    Desmin の背景知識

    The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G0/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation.

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