DBI Proteins, Antibodies, cDNA Clones Research Reagents

All DBI reagents are produced in house and quality controlled, including 2 DBI Antibody, 30 DBI Gene, 1 DBI Protein, 2 DBI qPCR. All DBI reagents are ready to use.

DBI Protein (1)

    DBI Antibody (2)

      DBI cDNA Clone (30)

      BC062996

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_007830.4

      クローニングベクター cDNA 製品

      In lentiviral vector

      DBI の背景知識

      The diazepam binding inhibitor (DBI), alternatively known as the acyl-CoA binding protein (ACBP), is involved in multiple biological actions. The polypeptide binds to the peripheral, or mitochondrial, benzodiazepine receptor and facilitates transport of cholesterol to the inner membrane to stimulate steroid synthesis. Through this action, DBI indirectly modulates gamma-aminobutyric acid (GABA)-mediated inhibitory neurotransmission. DBI can be postulated as a candidate gene for psychiatric phenotypes including anxiety, mood, and psychotic disorders. Diazepam Binding Inhibitor (DBI), also called acyl-CoA binding protein (ACBP), is a ubiquitously expressed protein originally identified based on its ability to displace diazepam from its binding site on the GABAA receptor. The mutant allele of the DBI was one of the risk factors for alcohol dependence as for the rs2276596 polymorphism.

      Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.