CROT Proteins, cDNA Clones Research Reagents

All CROT reagents are produced in house and quality controlled, including 45 CROT Gene, 1 CROT Lysate, 1 CROT Protein, 2 CROT qPCR. All CROT reagents are ready to use.

CROT Protein (1)

    CROT cDNA Clone (45)

    NM_021151.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_023733.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_031987.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    XM_006236005.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    CROT qPCR Primer (2)

    CROT Lysate (1)

      CROT の背景知識

      Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate the transport of medium- and long-chain fatty acids through the peroxisomal and mitochondrial membranes. It is physiologically inhibited by malonyl-CoA. COT also has functions in efficiently converting one of the end products of the peroxisomal beta-oxidation of pristanic acid, 4, 8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.

      CROT の参考文献

      • Ferdinandusse S, et al. (1999) Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta-oxidation of branched-chain fatty acids. Biochem Biophys Res Commun. 263 (1): 213-8.
      • Feike R, et al. (2000) Genomics of the Human Carnitine Acyltransferase Genes. Molecular Genetics and Metabolism. 71 (1-2): 139-53.
      • Montserrat Morillas, et al. (2002) Structural Model of a Malonyl-CoA-binding Site of Carnitine Octanoyltransferase and Carnitine Palmitoyltransferase I. The Journal of Biological Chemistry, 277: 11473-80.

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