COQ7 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All COQ7 reagents are produced in house and quality controlled, including 4 COQ7 Antibody, 1 COQ7 ELISA, 45 COQ7 Gene, 1 COQ7 Lysate, 1 COQ7 Protein, 3 COQ7 qPCR. All COQ7 reagents are ready to use.

COQ7 Protein (1)

    COQ7 Antibody (4)

      COQ7 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(1)

      COQ7 cDNA Clone (45)

      BC003185

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_009940.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_012785.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      COQ7 Lysate (1)

        COQ7 の背景知識

        Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical, and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site, a phosphorylation site for protein kinase C and another for casein kinase II, and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.

        COQ7 の参考文献

        • Ewbank J.J., et al., 1997, Science. 275: 980-3.
        • Vajo Z., et al., 1999, Mamm. Genome. 10: 1000-4.
        • Wiemann S., et al., 2001, Genome Res. 11: 422-35.
        • Stenmark,P. et al., 2001, J Biol Chem. 276 (36): 33297-300.
        • Martin J., et al., 2004, Nature. 432: 988-94. 

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