COL4A3BP Proteins, Antibodies, cDNA Clones Research Reagents

All COL4A3BP reagents are produced in house and quality controlled, including 2 COL4A3BP Antibody, 15 COL4A3BP Gene, 1 COL4A3BP IP Kit, 1 COL4A3BP Lysate, 1 COL4A3BP Protein, 1 COL4A3BP qPCR. All COL4A3BP reagents are ready to use.

COL4A3BP Protein (1)

    COL4A3BP Antibody (2)

      COL4A3BP cDNA Clone (15)

      BC000102

      クローニングベクター cDNA 製品

      In lentiviral vector

      COL4A3BP qPCR Primer (1)

      COL4A3BP Lysate (1)

        COL4A3BP の背景知識

        COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intracellular trafficking of ceramide in a non-vesicular manner. One isoform of COL4A3BP is also involved in ceramide intracellular transport. COL4A3BP specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. An autoimmune response directed at this antigen can cause goodpasture disease.

        COL4A3BP の参考文献

        • Rual JF, et al. (2005) Towards a proteome-scale map of the human protein-protein interaction network. Nature. 437(7062):1173-8.
        • Granero F, et al. (2005) A human-specific TNF-responsive promoter for Goodpasture antigen-binding protein. FEBS J. 272(20):5291-305.
        • Longo I, et al. (2006) Autosomal recessive Alport syndrome: an in-depth clinical and molecular analysis of five families. Nephrol Dial Transplant. 21(3):665-71.

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