Cofilin 2 Proteins, Antibodies, cDNA Clones Research Reagents

All Cofilin 2 reagents are produced in house and quality controlled, including 2 Cofilin 2 Antibody, 45 Cofilin 2 Gene, 1 Cofilin 2 IP Kit, 1 Cofilin 2 Protein, 3 Cofilin 2 qPCR. All Cofilin 2 reagents are ready to use.

Cofilin 2 Protein (1)

    Cofilin 2 Antibody (2)

      Cofilin 2 cDNA Clone (45)

      NM_021914.7

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_007688.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001108982.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      Cofilin 2 の背景知識

      Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.

      Cofilin 2 の参考文献

      • Aizawa H, et al. (2001) Cofilin-2, a novel type of cofilin, is expressed specifically at aggregation stage of Dictyostelium discoideum development. Genes Cells. 6 (10): 913-21.
      • Papalouka V, et al. (2009) Muscle LIM protein interacts with cofilin 2 and regulates F-actin dynamics in cardiac and skeletal muscle. Papalouka V, Mol Cell Biol. 29 (22): 6046-58.

      Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.