CNTF Proteins, Antibodies, cDNA Clones Research Reagents

All CNTF reagents are produced in house and quality controlled, including 8 CNTF Antibody, 18 CNTF Gene, 3 CNTF Protein, 2 CNTF qPCR. All CNTF reagents are ready to use.

CNTF Protein (3)

    CNTF Antibody (8)

      CNTF cDNA Clone (18)


      In expression vector

      In lentiviral vector


      クローニングベクター cDNA 製品


      クローニングベクター cDNA 製品

      In lentiviral vector

      CNTF qPCR Primer (2)

      CNTF の背景知識

      Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. Ciliary neurotrophic factor (CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit (CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocyteands may be relevant in reducing tissue destruction during inflammatory attacks. CNTF also is a survival factor for neurons of the peripheral sensory sympathetic and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.

      CNTF の参考文献

      • Dutt K, et al. (2010) Ciliary neurotrophic factor: a survival and differentiation inducer in human retinal progenitors. In Vitro Cell Dev Biol Anim. 46 (7) : 635-46.
      • Lam A, et al.(1991) Sequence and structural organization of the human gene encoding ciliary neurotrophic factor. Gene 102 (2) : 271–6.
      • Bazan JF. ( 1991) Neuropoietic cytokines in the hematopoietic fold. Neuron 7 (2) : 197–208.

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