CLEC-1 Proteins, cDNA Clones Research Reagents

All CLEC-1 reagents are produced in house and quality controlled, including 39 CLEC-1 Gene, 3 CLEC-1 Lysate, 3 CLEC-1 Protein, 3 CLEC-1 qPCR. All CLEC-1 reagents are ready to use.

CLEC-1 Protein (3)

    CLEC-1 cDNA Clone (39)

    BC039072

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_175526.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_001109253.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    CLEC-1 Lysate (3)

      CLEC-1 の背景知識

      CLEC1A, also known as CLEC-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC1A contains 1 C-type lectin domain and is expressed preferentially in dendritic cells. It may play a role in regulating dendritic cell function. CLEC1A gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splice variants have been described but their biological nature has not been determined. CLEC1A is found to be not only expressed in dendritic cells, but also in endothelial cells and in the latter aspect resembles the LOX-1 gene.

      CLEC-1 の参考文献

      • Ebner S, et al. (2003) volutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily. Proteins. 53(1):44-55.
      • Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
      • Drickamer K. (1999) C-type lectin-like domains. Curr Opin Struct Biol. 9(5):585-90.

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