CEL Proteins, Antibodies, cDNA Clones Research Reagents

All CEL reagents are produced in house and quality controlled, including 3 CEL Antibody, 27 CEL Gene, 1 CEL Lysate, 1 CEL Protein, 2 CEL qPCR. All CEL reagents are ready to use.

CEL Protein (1)

    CEL Antibody (3)

      CEL cDNA Clone (27)

      NM_001807.4

      In expression vector

      NM_009885.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_016997.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      CEL qPCR Primer (2)

      CEL Lysate (1)

        CEL の背景知識

        CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL cause maturity-onset diabetes of the young as well as pancreatic exocrine dysfunction. The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail.

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