CD5L Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CD5L reagents are produced in house and quality controlled, including 7 CD5L Antibody, 2 CD5L ELISA, 26 CD5L Gene, 2 CD5L Lysate, 2 CD5L Protein, 2 CD5L qPCR. All CD5L reagents are ready to use.

CD5L Protein (2)

    CD5L Antibody (7)

      CD5L ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(2)

      CD5L cDNA Clone (26)

      NM_005894.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_009690.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      CD5L Lysate (2)

        CD5L の背景知識

        CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

        CD5L の参考文献

        • Resnick, D. et al., 1994, Trends Biochem. Sci. 19: 5-8.
        • Gebe, J. A. et al., 1997, J. Biol. Chem. 272 (10): 6151–6158.
        • Sarrias, M.R. et al., 2004, Crit. Rev. Immunol. 24: 1-37.
        • Mukhopadhyay, S. and Gordon, S., 2004, Immunobiology 209: 39-49.
        • Sarrias, M. R. et al.,2005, J. Biol. Chem. 280 (42): 35391–35398.

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