CD151 Antibodies, cDNA Clones Research Reagents

All CD151 reagents are produced in house and quality controlled, including 3 CD151 Antibody, 53 CD151 Gene, 3 CD151 qPCR. All CD151 reagents are ready to use.

CD151 Antibody (3)

    CD151 cDNA Clone (53)

    BC001374

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_001111049.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_022523.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    XM_005576813.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    CD151 の背景知識

    Tspan8 and CD151 are metastasis-promoting tetraspanins and a knockdown (kd) of Tspan8 or CD151 and most pronounced of both tetraspanins affects the metastatic potential of the rat pancreatic adenocarcinoma line ASML. CD151- and Tspan8-competent tumor exosomes support matrix degradation, reprogram stroma and hematopoietic cells and drive non-metastatic ASML-CD151/Tspan8kd cells towards a motile phenotype. Distinct contributions of CD151 and Tspan8 to skin wound healing rely on preferentially CD151 anchoring basal keratinocytes and Tspan8 promoting motility. Transfection of non-permissive PK-15 cells with porcine CD151 cDNA conferred the susceptibility to PRRSV infection, indicating an important role of the porcine CD151 in PRRSV infection of porcine cells.

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