CD14 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CD14 reagents are produced in house and quality controlled, including 40 CD14 Antibody, 1 CD14 ELISA, 65 CD14 Gene, 7 CD14 Lysate, 7 CD14 Protein, 3 CD14 qPCR. All CD14 reagents are ready to use.

CD14 Protein (7)

    CD14 Antibody (40)

      CD14 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(1)

      CD14 cDNA Clone (65)

      NM_000591.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_009841.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_021744.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      XM_004802907.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001130433.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      CD14 Lysate (7)

        CD14 の背景知識

        The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

        CD14 の参考文献

        • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
        • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
        • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
        • SD Wright, et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249 (4975): 1431-3.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.