CCL14 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CCL14 reagents are produced in house and quality controlled, including 5 CCL14 Antibody, 1 CCL14 ELISA, 13 CCL14 Gene, 2 CCL14 Protein, 1 CCL14 qPCR. All CCL14 reagents are ready to use.

CCL14 Protein (2)

    CCL14 Antibody (5)

      CCL14 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(1)

      CCL14 cDNA Clone (13)

      NM_032963.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      CCL14 qPCR Primer (1)

      CCL14 の背景知識

      CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration.

      CCL14 の参考文献

      • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
      • Knappe S, et al. (1996) HCC-1, a novel chemokine from human plasma. J Exp Med. 183: 295-9.
      • Naruse, et al. (1996) A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 34: 236-40.

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