Cbl-c Proteins, Antibodies Research Reagents

All Cbl-c reagents are produced in house and quality controlled, including 2 Cbl-c Antibody, 1 Cbl-c Lysate, 1 Cbl-c Protein. All Cbl-c reagents are ready to use.

Cbl-c Protein (1)

    Cbl-c Antibody (2)

      Cbl-c Lysate (1)

        Cbl-c の背景知識

        CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.

        Cbl-c の参考文献

        • Kim M. et al., 1999, Gene. 239 (1): 145-54.
        • Courbard JR. et al., 2003, J. Biol. Chem. 277 (47): 45267-75.
        • Keane MM. et al., 1999, Oncogene. 18 (22): 3365-75.

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