Caveolin-1 cDNA Clones Research Reagents

All Caveolin-1 reagents are produced in house and quality controlled, including 41 Caveolin-1 Gene, 2 Caveolin-1 qPCR. All Caveolin-1 reagents are ready to use.

Caveolin-1 cDNA Clone (41)

NM_001753.3

クローニングベクター cDNA 製品

In lentiviral vector

NM_001243064.1

クローニングベクター cDNA 製品

In lentiviral vector

NM_031556.2

クローニングベクター cDNA 製品

In lentiviral vector

NM_133651.2

クローニングベクター cDNA 製品

Caveolin-1 の背景知識

CAV1/Caveolin1, an integral membrane protein, is involved in caveolae function and cellular signaling pathways. The phosphorylated CAV1 functions to activate autophagy through binding to the BECN1/VPS34 complex under oxidative stress and to protect against ischemic damage. Genetic deletion of Cav1 significantly blunts adrenergic-stimulated ATP release and vasoconstriction, with no direct influence on endothelium-dependent vasodilation or cardiac function. Caveolin-1 (CAV1) is known for its role as both a tumor suppressor and an oncogene, harboring a highly context-dependent role within a myriad of malignancies and cell types. In an immunological context, dysregulation of CAV1 expression has been shown to alter immunological signaling functions and suggests a pivotal role for CAV1 in the facilitation of proper immune responses.

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