CASP8/ALPS2B cDNA Clones Research Reagents

All CASP8/ALPS2B reagents are produced in house and quality controlled, including 16 CASP8/ALPS2B Gene, 1 CASP8/ALPS2B qPCR. All CASP8/ALPS2B reagents are ready to use.

CASP8/ALPS2B cDNA Clone (16)

NM_033355.3

クローニングベクター cDNA 製品

In lentiviral vector

NM_033356.3

クローニングベクター cDNA 製品

CASP8/ALPS2B qPCR Primer (1)

CASP8/ALPS2B の背景知識

Caspase 8 is a cysteine dependent endoprotease that plays a key role in the regulation of apoptosis (also referred as programmed cell death), an event which is known to be essential in growth and development of embryo, and maintenance of tissue homeostasis. Caspases are broadly classified as apoptosis or inflammation regulatory caspases based on their role in respective processes. Of those known, caspase - 3, -6, -7, -8 and -9 are categorized as apoptotic caspases, whereas caspase -1, -4, -5 and -12 are grouped as inflammatory caspases. The apoptotic caspases are further classified into initiator caspases (caspase -8 and -9) and effecter caspases (caspase -3, -6 and -7) based on their role in transducing the apoptotic signals emanating at the cell membrane.

CASP8/ALPS2B の参考文献

  • Menon U, Raghuram P H, Kannan K, et al. Mutation Analysis of the Dimer Forming Domain of the Caspase 8 Gene in Oral Submucous Fibrosis and Squamous Cell Carcinomas[J]. Asian Pacific journal of cancer prevention: APJCP, 2014, 16(11): 4589-4592.

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