Carbonic Anhydrase XIV Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Carbonic Anhydrase XIV reagents are produced in house and quality controlled, including 8 Carbonic Anhydrase XIV Antibody, 1 Carbonic Anhydrase XIV ELISA, 25 Carbonic Anhydrase XIV Gene, 1 Carbonic Anhydrase XIV IP Kit, 2 Carbonic Anhydrase XIV Lysate, 2 Carbonic Anhydrase XIV Protein, 2 Carbonic Anhydrase XIV qPCR. All Carbonic Anhydrase XIV reagents are ready to use.

All Carbonic Anhydrase XIV Reagents

Carbonic Anhydrase XIV Protein (2)

    Carbonic Anhydrase XIV Antibody (8)

      Carbonic Anhydrase XIV ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(1)

      Carbonic Anhydrase XIV cDNA Clone (25)

      NM_012113.1
      NM_011797.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      Carbonic Anhydrase XIV Lysate (2)

        Carbonic Anhydrase XIV の背景知識

        The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain.

        Carbonic Anhydrase XIV の参考文献

        • Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
        • Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1):1-20.
        • Parkkila S, et al. (2001) Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain. PNAS. 98(4): 1918-23.

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