BPIFA2 Proteins, cDNA Clones Research Reagents

All BPIFA2 reagents are produced in house and quality controlled, including 13 BPIFA2 Gene, 2 BPIFA2 Lysate, 2 BPIFA2 Protein, 1 BPIFA2 qPCR. All BPIFA2 reagents are ready to use.

BPIFA2 Protein (2)

    BPIFA2 cDNA Clone (13)

    BC065726

    クローニングベクター cDNA 製品

    In lentiviral vector

    BPIFA2 qPCR Primer (1)

    BPIFA2 Lysate (2)

      BPIFA2 の背景知識

      C20orf70 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 3' end. 80 bp of this gene are antisense to spliced gene glopa, raising the possibility of regulated alternate expression. C20orf70 is expected to have molecular function (lipid binding) and to localize in extracellular region. It is a salivary protein of unknown function.

      BPIFA2 の参考文献

      • Lamesch P, et al. (2007) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics. 89(3):307-15.
      • Vargas PA, et al. (2008) Expression of PLUNC family members in benign and malignant salivary gland tumours. Oral Dis. 14(7):613-9.
      • Bingle L, et al. (2009) Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein. Histochem Cell Biol. 132(3):339-49.

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