BPHL Proteins, Antibodies, cDNA Clones Research Reagents

All BPHL reagents are produced in house and quality controlled, including 1 BPHL Antibody, 41 BPHL Gene, 1 BPHL IP Kit, 1 BPHL Protein, 1 BPHL qPCR. All BPHL reagents are ready to use.

BPHL Protein (1)

    BPHL Antibody (1)

      BPHL cDNA Clone (41)


      クローニングベクター cDNA 製品

      In lentiviral vector


      クローニングベクター cDNA 製品

      In lentiviral vector


      クローニングベクター cDNA 製品

      In lentiviral vector

      BPHL qPCR Primer (1)

      BPHL の背景知識

      BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.

      BPHL の参考文献

      • Lai L. et al., 2008, J Biol Chem. 283 (14): 9318-27.
      • Davila S. et al., 2010, Genes Immun. 11 (3): 232-8.
      • Hendrickson SL. et al., 2010, PLoS One. 5 (9): e12862.

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