beta Defensin 1/DEFB1 Proteins, cDNA Clones Research Reagents

All beta Defensin 1/DEFB1 reagents are produced in house and quality controlled, including 13 beta Defensin 1/DEFB1 Gene, 1 beta Defensin 1/DEFB1 Lysate, 1 beta Defensin 1/DEFB1 Protein, 1 beta Defensin 1/DEFB1 qPCR. All beta Defensin 1/DEFB1 reagents are ready to use.

beta Defensin 1/DEFB1 Protein (1)

    beta Defensin 1/DEFB1 cDNA Clone (13)

    BC047677

    クローニングベクター cDNA 製品

    In lentiviral vector

    beta Defensin 1/DEFB1 qPCR Primer (1)

    beta Defensin 1/DEFB1 Lysate (1)

      beta Defensin 1/DEFB1 の背景知識

      The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. One such strategy is to reduce the production of the antimicrobial peptide beta-defensin 1 (DEFB1) by host epithelial cells. Beta-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity.

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