Band 3/SLC4A1 Antibodies, cDNA Clones Research Reagents

All Band 3/SLC4A1 reagents are produced in house and quality controlled, including 2 Band 3/SLC4A1 Antibody, 28 Band 3/SLC4A1 Gene, 2 Band 3/SLC4A1 qPCR. All Band 3/SLC4A1 reagents are ready to use.

Band 3/SLC4A1 Antibody (2)

    Band 3/SLC4A1 cDNA Clone (28)

    NM_000342

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_011403.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_012651.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    Band 3/SLC4A1 の背景知識

    The Band 3 (AE1, SLC4A1) membrane protein is found in red blood cells and in kidney where it functions as an electro-neutral chloride/bicarbonate exchanger. Primary distal renal tubular acidosis (dRTA) caused by mutations of the SLC4A1 gene, which encodes for erythroid and kidney isoforms of anion exchanger, shows marked difference in inheritance patterns and clinical features in different parts of the world. Distal renal tubular acidosis caused by missense mutations in kidney isoform of anion exchanger 1 (kAE1/SLC4A1), the basolateral membrane Cl(-)/HCO3(-) exchanger of renal alpha-intercalated cells, has been extensively investigated in heterologous expression systems.

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