ASGR2 Proteins, Antibodies, cDNA Clones Research Reagents

All ASGR2 reagents are produced in house and quality controlled, including 3 ASGR2 Antibody, 26 ASGR2 Gene, 1 ASGR2 Lysate, 1 ASGR2 Protein, 1 ASGR2 qPCR. All ASGR2 reagents are ready to use.

ASGR2 Protein (1)

    ASGR2 Antibody (3)

      ASGR2 cDNA Clone (26)

      NM_001201352.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_080913.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      ASGR2 qPCR Primer (1)

      ASGR2 Lysate (1)

        ASGR2 の背景知識

        ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit.

        ASGR2 の参考文献

        • Davila S, et al. (2010) New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. 11(3):232-8.
        • Zhang X, et al. (2011) Asialoglycoprotein receptor interacts with the preS1 domain of hepatitis B virus in vivo and in vitro. Arch Virol. 156(4):637-45.
        • Guy CS, et al. (2011) Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor. Hepatology. 54(3):1043-50.

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