ARL2BP Proteins, Antibodies, cDNA Clones Research Reagents

All ARL2BP reagents are produced in house and quality controlled, including 4 ARL2BP Antibody, 31 ARL2BP Gene, 1 ARL2BP Protein, 2 ARL2BP qPCR. All ARL2BP reagents are ready to use.

ARL2BP Protein (1)

    ARL2BP Antibody (4)

      ARL2BP cDNA Clone (31)

      BC003087

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_024191.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001024906.1

      クローニングベクター cDNA 製品

      ARL2BP の背景知識

      ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. ARL2BP, together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. ARL2BP may play a role as an effector of ARL2.

      ARL2BP の参考文献

      • Qiu J. et al., 2011, PLoS Pathog. 7 (8): e1002193.
      • Taniuchi K. et al., 2012, PLoS One. 7 (4): e35674.
      • Taniuchi K. et al., 2012, Neoplasia. 14 (5): 440-50.

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