ApoM Proteins, cDNA Clones Research Reagents

All ApoM reagents are produced in house and quality controlled, including 14 ApoM Gene, 1 ApoM Lysate, 2 ApoM Protein. All ApoM reagents are ready to use.

ApoM Protein (2)

    ApoM cDNA Clone (14)


    In expression vector


    クローニングベクター cDNA 製品

    In lentiviral vector

    ApoM Lysate (1)

      ApoM の背景知識

      ApoM (apolipoprotein M) is an apolipoprotein and member of the lipocalin protein family. The lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They have an eight-stranded, antiparallel, symmetrical _-barrel fold, which is in essence a beta sheet which has been rolled into a cylindrical shape. Inside this barrel is located a ligand binding site. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins have been associated with many biological processes, among them immune response, pheromone transport, biological prostaglandin synthesis, retinoid binding, and cancer cell interactions. Lipocalins are comparatively small in size, and are thus less complicated to study as opposed to large, bulky proteins. They can also bind to various ligands for different biological purposes. ApoM is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. ApoM is involved in lipid transport and can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.

      ApoM の参考文献

      • Xu N, et al. (1999) A novel human apolipoprotein (apoM). J Biol Chem. 274(44):31286-90.
      • Duan J, et al. (2001) Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis. FEBS Lett. 49 (1-2):127-32.
      • Albertella MR, et al. (1997) Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). Genomics. 36(2):240-51.

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