APLP1 Proteins, Antibodies, cDNA Clones Research Reagents

All APLP1 reagents are produced in house and quality controlled, including 3 APLP1 Antibody, 26 APLP1 Gene, 2 APLP1 Lysate, 2 APLP1 Protein, 2 APLP1 qPCR. All APLP1 reagents are ready to use.

APLP1 Protein (2)

    APLP1 Antibody (3)

      APLP1 cDNA Clone (26)

      BC012889

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_007467.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      APLP1 Lysate (2)

        APLP1 の背景知識

        APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

        APLP1 の参考文献

        • Wasco W. et al., 1993, Genomics. 15 (1): 237-9.
        • Needham BE. et al., 2008, J Pathol. 215 (2): 155-63.
        • Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8.
        • Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.

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