AMPK Antibodies, cDNA Clones Research Reagents

PRKAA2 (Protein Kinase AMP-Activated Catalytic Subunit Alpha 2) is a protein coding gene located on human chromosome 1p32.2. PRKAA2 is also known as AMPK, AMPK2, PRKAA and AMPKa2. The human PRKAA2 gene encodes a 62320 Da protein containing 552 amino acids. The PRKAA2 protein is biasedly expressed in heart, kidney and other tissues. Among its related pathways are Organelle biogenesis and maintenance and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. PRKAA2 is related to transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. PRKAA1 is an important paralog of PRKAA2 gene. PRKAA2 is associated with some diseases, including Peutz-Jeghers Syndrome and Ischemia.

AMPK Antibody (1)

    AMPK cDNA Clone (17)

    NM_006252.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_178143.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    AMPK qPCR Primer (1)

    AMPK の背景知識

    PRKAA2, the gene that encodes the alpha2 catalytic subunit of AMPK, showed be involved in the glucose and lipid metabolism. The PRKAA2 genotypes of 406 T2DM patients and 214 controls from the Chinese Han population were determined with regard to SNPs rs10789038, rs2796498 and rs2746342. Polymorphisms in rs10789038 and rs2796498 are associated with the susceptibility to T2DM, and rs2796498 may be related to diabetic nephropathy.

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