AMIGO2 Proteins, Antibodies, cDNA Clones Research Reagents

All AMIGO2 reagents are produced in house and quality controlled, including 4 AMIGO2 Antibody, 26 AMIGO2 Gene, 1 AMIGO2 Lysate, 2 AMIGO2 Protein, 1 AMIGO2 qPCR. All AMIGO2 reagents are ready to use.

AMIGO2 Protein (2)

    AMIGO2 Antibody (4)

      AMIGO2 cDNA Clone (26)

      BC047595

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001164563.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      AMIGO2 qPCR Primer (1)

      AMIGO2 Lysate (1)

        AMIGO2 の背景知識

        AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It belongs to the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus.

        AMIGO2 の参考文献

        • Rouhiainen A, et al. (2003) AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J Cell Biol. 160:963-73.
        • Kikkawa Y, et al. (2003) Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons. J Neurosci. 23:5887-96.
        • Bassi R, et al. (2004) DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity. Oncogene 23:5056-67.

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