5HT2B/HTR2B Antibodies, cDNA Clones Research Reagents

HTR2B (5-Hydroxytryptamine Receptor 2B, also known as 5-HT2B; 5-HT-2B; 5-HT(2B)), located on 2q37.1, is a Protein Coding gene. The gene produces a 54298 Da protein composed of 481 amino acids. The encoded protein is one of the several different receptors for 5-hydroxytryptamine (serotonin). The HTR2B receptor may contribute to the regulation of human glucagon and glucose homeostasis and the interplay between glucagon and insulin secretion. Diseases such as Heart Valve Disease and Ocular Hypotension are associated with HTR2B. The related pathways of HTR2B include RET signaling and Signaling by GPCR.

5HT2B/HTR2B Antibody (1)

    5HT2B/HTR2B cDNA Clone (14)

    NM_000867.4

    In expression vector

    NM_008311.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    5HT2B/HTR2B qPCR Primer (1)

    5HT2B/HTR2B の背景知識

    HTR2B (5-Hydroxytryptamine Receptor 2B, also known as 5-HT2B) is a Protein Coding gene. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Besides its role as a neurotransmitter, serotonin (5-hydroxytryptamine, 5HT) regulates inflammation and tissue repair via a set of receptors (5HT(1-7)) whose pattern of expression varies among cell lineages. Reduced 5-HT2B receptor function at low or normal testosterone levels may be protective of obesity. The 5-HT2B receptor may contribute to the regulation of human glucagon and glucose homeostasis and the interplay between glucagon and insulin secretion. Diseases associated with HTR2B include Heart Valve Disease and Ocular Hypotension.

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