FGF2 Protein, Mouse, Recombinant (His Tag)

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FGF2 Protein, Mouse, Recombinant (His Tag): 製品情報

純度
> 95 % as determined by SDS-PAGE.
内毒素
Please contact us for more information.
活性
Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts.
The ED50 for this effect is typically 0.1-0.6 ng/mL.
タンパク質の構築
A DNA sequence encoding the mouse Fgf2 (NP_032032.1) (Ala11-Ser154) was expressed with a polyhistidine tag at the N-terminus.
NP No.
発現ホスト
E. coli
Mouse
予測N末端
Met
分子量
The recombinant mouse Fgf2 consists 162 amino acids and predicts a molecular mass of 18.5 kDa.
バッファー
Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
配送
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
安定性 & 保存条件
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
再構成
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

FGF2 Protein, Mouse, Recombinant (His Tag): 画像

Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/mL.

FGF2 Protein, Mouse, Recombinant (His Tag): 別名

bFGF Protein, Mouse; Fgf-2 Protein, Mouse; Fgfb Protein, Mouse

FGF2 背景情報

Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.

bFGF/FGF2 Protein & Antibody Products

完全な名称
fibroblast growth factor 2 (basic)
参考文献
  • Takayama S,et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.
  • Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.
  • Zhang Y,et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.
  • Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2
    Author
    Nadanaka, S;Kitagawa, H;
    Year
    2018
    Journal
    Biochim. Biophys. Acta
    Application
    binding (to cells)
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