phospho-Serine/phospho-Threonine Binding Proteins

The first phosphoserine/threonine-binding molecules that were identified were members of a family of dimeric proteins called 14-3-3 that were first identified as abundant polypeptides of unknown function in brain; they were later identified as activators of tryptophan and tyrosine hydroxylase and as inhibitors or activators of PKCs. Mammalian cells contain 7 distinct 14-3-3 gene products (denoted β, γ, e, η, σ, t, and ζ), while plants and fungicontain between 2 and 15. Several of the mammalian 14-3-3 isotypes are subject to phosphorylation, although the role that phosphorylation plays in 14-3-3 function remains speculative.

Sino Biological lists the classification tree of phospho-Serine/phospho-Threonine Binding Proteins, click to see all the related molecules/targets and research reagents of them.

phospho-Serine/phospho-Threonine Binding Proteins

phospho-Serine/phospho-Threonine Binding Proteins