Intracellular Kinases

Protein kinases transfer phosphate groups from ATP to serine, threonine, or tyrosine residues on protein peptide substrates, directly affecting the activity and function of the target. Radiolabel studies suggest that approximately 30% of proteins in eukaryotic cells are subject to phosphorylation. Kinase activity, a crucial post-translational modification, regulates a broad range of cellular activities including the cell cycle, differentiation, metabolism, and neuronal communication. In addition, abnormal activity of Akt, ERK, JNK, PKC, PKA, p38, and other MAPK are implicated in many disease states. R&D Systems offers a range of quality products for the detection of protein phosphorylation, which include kinase activity assays, phospho-specific antibodies, ELISA, and more.

Sino Biological lists the classification tree of Intracellular Kinases, click to see all the related molecules/targets and research reagents of them.

Intracellular Kinases

Intracellular Kinases

Akt Isoforms

Akt Isoforms

AMPK (AMP-activated Protein Kinases)

AMPK (AMP-activated Protein Kinases)

Creatin Kinase

Creatin Kinase

Cyclin-Dependent Protein Kinases (CDKs)

Cyclin-Dependent Protein Kinases (CDKs)

DYRKs (Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinases)

DYRKs (Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinases)

ERK (Extracellular Signal-regulated Kinases)

ERK (Extracellular Signal-regulated Kinases)

GRKs (G Protein-coupled Receptor Kinases)

GRKs (G Protein-coupled Receptor Kinases)

IkB Kinase (IKK)

IkB Kinase (IKK)

IRAK Family

IRAK Family

Jak Kinases

Jak Kinases

Mitogen-Activated Protein Kinase Kinases (MEKs/MKKs)

Mitogen-Activated Protein Kinase Kinases (MEKs/MKKs)

MSK

MSK

p38 MAP Kinases

p38 MAP Kinases

PAK (p21-activated Kinases)

PAK (p21-activated Kinases)

PI 3-Kinases (Phosphoinositide 3-Kinases)

PI 3-Kinases (Phosphoinositide 3-Kinases)

PKA Isoforms

PKA Isoforms

Polo-like Kinases

Polo-like Kinases

Ribosomal Protein S6 Kinases (RSK)

Ribosomal Protein S6 Kinases (RSK)

Src Kinases

Src Kinases