Calcium-binding Proteins and Related Molecules

Calcium-binding proteins have a vital role in calcium homeostasis by buffering and probably also have a neuroprotective function. Fluctuations in intracellular calcium (Ca2+) are central to orderly neurotransmission and the operation of a wide range of cellular functions. In the lateral BST, a few calbindin D-28k-immunoreactive neurons were scattered in a moderately stained neuropil. Staining of calretinin, another calcium-binding protein, was intense in the rostral pole of the lateral BST, continuous with the caudal ventral striatum. Small calretinin-immunoreactive cell bodies were observed in the lateral BST, but their dendrites could not be clearly visualized because of the intensity of background staining